Dr. James Wilson: You don't like yourself. But you do admire yourself. It's all you've got so you cling to it. You're so afraid if you change, you'll lose what makes you special.
Dr. James Wilson: Being miserable doesn't make you better than anybody else, House. It just makes you miserable.
Dr. James Wilson: Irene Adler. Christmas 2001. Sarcoid symptoms, but she didn't respond to methotrexate. I've never seen him so obsessed. He saved her with a last-minute Wegener's diagnosis, but the hours he put in... I thought it would kill him. And then... well, he fell for her, but it was too soon after Stacy and... It sounds silly, but Irene was the one who got away.
Dr. Lawrence Kutner: Really?
Dr. James Wilson: No, you idiots. House is just screwing with you.